Correlation of carbohydrate larval antigen (CarLA®) antibody response with parasitism in Ontario sheep

Authors

  • Emma A. Borkowski Department of Pathobiology, University of Guelph, Guelph, Ontario, NlG 2W1, Canada
  • Niel A. Karrow Department of Animal Biosciences, University of Guelph, Guelph, Ontario, NlG 2W1, Canada
  • Paula I. Menzies Department of Population Medicine, University of Guelph, Guelph, Ontario, NlG 2W1, Canada
  • Jacob Avula Department of Pathobiology, University of Guelph, Guelph, Ontario, NlG 2W1, Canada
  • Brandon N. Lillie Department of Pathobiology, University of Guelph, Guelph, Ontario, NlG 2W1, Canada
  • Andrew S. Peregrine Department of Pathobiology, University of Guelph, Guelph, Ontario, NlG 2W1, Canada

DOI:

https://doi.org/10.21423/aabppro20183255

Abstract

Gastrointestinal nematode parasites (GINs) are a significant cause of morbidity, mortality and loss of productivity on North American sheep farms. In light of the rising prevalence of anthelmintic resistance, selection of animals with a superior immune response to GINs has received considerable attention. In New Zealand, measurement of salivary antibody to a carbohydrate larval antigen (CarLA®, AgResearch Inc.) has been used successfully to identify sheep with superior immunity. However, climate and GIN epidemiology in Ontario are different from New Zealand, and sheep are generally not exposed to GINs for several months during housing over winter. To date, CarLA® has not been evaluated in North America. The purpose of this study was to determine whether Car LA® correlates with parasite burden under temperate grazing conditions in Ontario.

Cover image of the 51st Conference Proceedings: A man riding on a pale horse herding cattle on a semi-arid pasture

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Published

2018-09-13

Issue

2018

Section

AASRP Research Summaries