A randomized clinical trial assessing the use of a single injection of dexamethasone combined with oral propylene glycol therapy for the treatment of hyperketonemia
Keywords:hyperketonemia, dairy cattle, BHBA
The treatment of hyperketonemia (HK, blood β-hydroxybutyrate (BHBA) > 1.2 mmol/L) with oral propylene glycol has proven benefits. Parenteral administration of glucocorticoids has been suggested as an adjunctive therapy; however it has not been assessed in a randomized controlled trial. The objective of this research was to evaluate the effect on the probability of cure, risk of subsequent disease, and milk production of a 1-time intramuscular injection of dexamethasone as an adjunctive therapy for HK.