Effect of injectable trace minerals (zinc, manganese, selenium, and copper) on the humoral and cell-mediated immune responses to vaccine antigens following administration of a modified-live viral vaccine in dairy calves

Authors

  • R. A. Palomares University of Georgia, College of Veterinary Medicine, Department of Population Health, Athens, GA 30602; 2\Jniversity of Georgia, College of Veterinary Medicine, Department of Large Animal Medicine Athens GA 30602
  • F. Moliere University of Georgia, College of Veterinary Medicine, Department of Population Health Athens GA 30602
  • L. J. Havenga Multimin USA, Fort Collins, CO 80528
  • A. R. Woolums University of Georgia, College of Veterinary Medicine, Department of Large Animal Medicine, Athens, GA 30602
  • N. A. Norton University of Georgia, College of Veterinary Medicine, Department of Population Health, Athens, GA 30602
  • B. Credille University of Georgia, College of Veterinary Medicine, Department of Population Health, Athens, GA 30602; 2\Jniversity of Georgia, College of Veterinary Medicine, Department of Large Animal Medicine Athens GA 30602
  • S. J. Clifton University of Georgia, College of Veterinary Medicine, Department of Population Health, Athens, GA 30602
  • A. B. Sigmund University of Georgia, College of Veterinary Medicine, Department of Population Health, Athens, GA 30602
  • C. E. Barber University of Georgia, College of Veterinary Medicine, Department of Population Health, Athens, GA 30602
  • M. L. Berger University of Georgia, College of Veterinary Medicine, Department of Population Health, Athens, GA 30602
  • M. J. Clark University of Georgia, College of Veterinary Medicine, Department of Population Health, Athens, GA 30602
  • M. A. Fratto University of Georgia, College of Veterinary Medicine, Department of Population Health, Athens, GA 30602
  • D. J. Hurley University of Georgia, College of Veterinary Medicine, Department of Population Health, Athens, GA 30602; 2\Jniversity of Georgia, College of Veterinary Medicine, Department of Large Animal Medicine Athens GA 30602

DOI:

https://doi.org/10.21423/aabppro20153648

Keywords:

trace minerals, dairy cattle, beef cattle, bovine herpesvirus, vaccine, bovine viral diarrhea virus, BHV1, parainfluenza virus 3, bovine respiratory syncytial virus

Abstract

The benefits of administering injectable trace minerals (ITM; Zn, Mn, Cu, and Se) on animal health and performance have been previously assessed in dairy and beef cattle. Previous studies demonstrated that ITM improved humoral immune response to bovine herpesvirus l(BHV-l) following administration of a modified live virus (MLV) vaccine in cattle. The objective of this study was to evaluate the effect of an ITM supplement containing zinc, manganese, selenium, and copper on the humoral and cell mediated immune (CMI) responses to individual vaccine antigens in dairy calves receiving a MLV vaccine containing bovine viral diarrhea virus (BVDV), BHV1, parainfluenza virus 3 (PI3V), and bovine respiratory syncytial virus (BRSV).

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2015-09-17

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