Microbial Safety of Ceftiofur and its Metabolites

Instability in the Right Places

Authors

  • Susan F. Kotarski Pharmacia Animal Health, Kalamazoo, MI 49001
  • Rex E. Hornish Pharmacia Animal Health, Kalamazoo, MI 49001
  • Walter J. Smolenski Pharmacia Animal Health, Kalamazoo, MI 49001
  • Sarah A. Salmon Pharmacia Animal Health, Kalamazoo, MI 49001
  • Scott A. Brown Pharmacia Animal Health, Kalamazoo, MI 49001
  • Fabian Kausche Pharmacia Animal Health, Kalamazoo, MI 49001
  • Edward J. Robb Pharmacia Animal Health, Kalamazoo, MI 49001

DOI:

https://doi.org/10.21423/aabppro20015217

Keywords:

Ceftiofur, cephalosporin, pathogens, microbiological safety, effectiveness

Abstract

Ceftiofur is a late-generation, injectable cephalosporin developed solely for veterinary therapeutic use. During the 12 years of field use, surveys suggest that the incidence of veterinary and food-borne pathogens with decreased susceptibility to ceftiofur is still very low. This paper assesses the microbiological safety of ceftiofur with respect to current susceptibility patterns of pathogens, and inherent chemical and biological factors that aid in maintaining its effectiveness.

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Published

2001-09-13

Issue

Section

Research Summaries - General