Minimum Inhibitory Concentration Determinations for Ceftiofur and Spectinomycin against Pasteurella multocida, Mannheimia spp. and Haemophilus somnus from France, The Netherlands, and Germany

Authors

  • S. A. Salmon Pharmacia Animal Health
  • J. L. Watts Pharmacia Animal Health
  • C. A. Van den Eede Pharmacia Animal Health
  • A. Bils Pharmacia Animal Health
  • F. Goldenstein Saint Joseph Hospital Foundation, Paris, France
  • J. Acar Saint Joseph Hospital Foundation, Paris, France
  • C. Kehrenberg Federal Research Centre for Agriculture, Celle, Germany
  • S. Schwartz Federal Research Centre for Agriculture, Celle, Germany

DOI:

https://doi.org/10.21423/aabppro20015270

Keywords:

Ceftiofur, cephalosporin, bovine respiratory disease

Abstract

Ceftiofur is an extended-spectrum cephalosporin approved in many countries worldwide for treatment of bovine respiratory disease (BRD), as well as respiratory disease of other animals. Ceftiofur has demonstrated excellent in vitro activity against bacteria of importance in BRD: Mannheimia spp., Pasteurella multocida, andHaemophilus somnus. Spectinomycin is an aminocyclitol antimicrobial agent. Spectinomycin sulfate was recently approved in the United States for treatment of BRD caused by P. multocida, Mannheimia spp., and H. somnus; approvals are currently pending in other countries. To determine the in vitro activity of ceftiofur and spectinomycin against recent BRD pathogens from France, The Netherlands and Germany, minimum inhibitory concentrations (MIC) were determined.

Cover image of the 34th Conference Proceedings: Four men on horseback lead a single cow through a pen. Yellow background.

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Published

2001-09-13

Issue

2001

Section

Posters