Immunohistochemical Test on Skin Biopsies as a Method for Detection of Cattle Persistently Infected with Bovine Viral Diarrhea Virus

Authors

  • Bruce W. Brodersen University of Nebraska, Institute of Agriculture and Natural Resources, Department of Veterinary and Biomedical Sciences, Lincoln, Nebraska
  • Amy K. White University of Nebraska, Institute of Agriculture and Natural Resources, Department of Veterinary and Biomedical Sciences, Lincoln, Nebraska
  • David R. Smith University of Nebraska, Institute of Agriculture and Natural Resources, Department of Veterinary and Biomedical Sciences, Lincoln, Nebraska

DOI:

https://doi.org/10.21423/aabppro19985756

Keywords:

persistently infected, bovine viral diarrhea virus, rapid method, BVDV antigen, immunohistochemical

Abstract

A novel rapid method for identification of cattle persistently infected (PI) with bovine viral diarrhea virus (BVDV) was examined. Individual cattle PI with BVDV serve as a source of infectious virus within cattle herds. Identification of cattle which are PI with BVDV is a clinical challenge, since many PI cattle appear clinically normal. BVDV infects a wide variety of tissues and cell types, particularly cells of the monocyte macrophage lineage. Cells of this lineage are present in the skin. BVDV antigen can be readily detected by the immunohistochemical (IHC) method.

Cover image of the 31st Conference Proceedings: A photo of Dr. Eric I. and Mrs. Mary Williams smiling in golden light. Yellow background.

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Published

1998-09-24

Issue

1998

Section

Research Summaries - Beef and General I & II

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