The development and testing of a vaccine for the prevention of infectious bovine keratoconjunctivitis

Authors

  • Kevin O'Connell School of Veterinary Medicine, University of California, Davis, Davis, CA 95616
  • Lisle George School of Veterinary Medicine, University of California, Davis, Davis, CA 95616

DOI:

https://doi.org/10.21423/aabppro19965986

Keywords:

protein cytotoxin, Moraxella bovis, concentrated, vaccine trial, efficacy, toxicity

Abstract

We have purified, concentrated and stabilized the protein cytotoxin from Moraxella bovis. The toxin is concentrated on a filter with a 500,000 kDa molecular weight cut off. Small proteins are removed by extensive diafiltration on the same filter. The cytotoxin is concentrated approximately 500 fold, and remains active after 5 months of freezing. A vaccine trial for toxicity and efficacy were performed.

Cover image of the 29th Conference Proceedings: A photo of the city skyline of San Diego, California. Yellow background.

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Published

1996-09-12

Issue

1996

Section

Posters