Evaluation of IBR Vaccine Virus Shedding After Parenteral Administration to Suckling Calves

Authors

  • Donna M. Gatewood Diamond Animal Health, 2538 SE 43rd Street, Des Moines, Iowa 50317
  • Phillip J. Sprino Diamond Animal Health, 2538 SE 43rd Street, Des Moines, Iowa 50317
  • W. Charles Ohnesorge Diamond Animal Health, 2538 SE 43rd Street, Des Moines, Iowa 50317
  • Benjamin P. All Diamond Animal Health, 2538 SE 43rd Street, Des Moines, Iowa 50317
  • Melisse M. Gray Diamond Animal Health, 2538 SE 43rd Street, Des Moines, Iowa 50317

DOI:

https://doi.org/10.21423/aabppro19965988

Keywords:

IBR vaccine, abortigenic, modified live IBR vaccines, shedding, transmission, immunosuppression, parenteral vaccination

Abstract

Many vaccine strains of IBR are assumed to be abortigenic. There is therefore concern about administering modified live IBR vaccines to suckling calves because of the possibility of shedding of the vaccine virus by vaccinates and subsequent transmission to the pregnant dam. The purpose of Phase I of this study was to show whether IBR MLV vaccine strain RT-22 causes virus shedding after parenteral vaccination of IBR-susceptible calves. Phase II of the study was designed to show whether immunosuppression 90 days after vaccination would result in recrudescence of the vaccine virus and subsequent viral shed.

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Published

1996-09-12

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