Studies on Serotype-Specific Regulation of Antigen Expression in Pasteurela Haemolytica
DOI:
https://doi.org/10.21423/aabppro19926612Keywords:
BRD, pleuropneumonia, shipping fever, Bovine respiratory diseaseAbstract
Bovine respiratory disease (BRD) remains a major economic problem for both the beef and dairy cattle industries in the U.S. (1). Recent estimates of the losses due to BRO exceed a billion dolars annually which is greater than all other diseases combined (2).
The most common sequel observed in BRD is a fulminating fibrinonecrotic pleuropneumonia called shipping fever or pneumonic pasteurellosis. Although BRD is a multifactorial disease involving interaction between a number of environmental factors, various viruses and bacteria, Pasteurella haemolytica biotype A serotype 1 (A1) also called serotype 1 (ST1) has been established as the primary agent involved in the pathogenesis of the pneumonia (3). P. haemolytica ST1 can be isolated in pure culture from typical pneumonic lesions of the disease (4).