Evaluation of An Associated Inactivated Vaccine Against Neonatal Diarrhoeas Caused by Colibacilli, Rotavirus and Coronavirus

Authors

  • G. Reynaud RHONE MERIEUX, 254 rue Marcel Mérieux, 69007 LYON, France
  • A. Brun RHONE MERIEUX, 254 rue Marcel Mérieux, 69007 LYON, France
  • F. Milward RHONE MERIEUX, 254 rue Marcel Mérieux, 69007 LYON, France
  • B. Saint-Marc RHONE MERIEUX, 254 rue Marcel Mérieux, 69007 LYON, France
  • J. Vandeputte RHONE MERIEUX, 254 rue Marcel Mérieux, 69007 LYON, France

DOI:

https://doi.org/10.21423/aabppro19926632

Keywords:

infectious diarrhoeas, control program, vaccination, viruses, rotavirus, coronavirus, inactivated vaccine, aluminium hydroxyde, saponin

Abstract

The major economic importance of neonatal infectious diarrhoeas in calves have justified for a few years the development of control programmes combining both sanitary and medical aspects [7]. The importance of immunity conferred through colostrum and milk has been demonstrated [1] [2] [8]. The vaccination of pregnant cows revealed, in the field, as the most efficient mean to reach a high colostrum and milk immunity [3] [4] [5] [10]. The etiology of neonatal infectious diarrhoeas in cattle is now well-determined different types of colibacilli having well-characterized attachment or virulence factors are now isolated; viruses, rotavirus and coronavirus, have also been evidenced [6] [9] [11] [12].

The authors present the results obtained during a controlled clinical trial by using an inactivated vaccine, adjuvanted with aluminium hydroxyde and saponin. This vaccine is indicated for vaccination of pregnant cows.

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Published

1992-08-31

Issue

Section

Immunology