Evaluation of An Associated Inactivated Vaccine Against Neonatal Diarrhoeas Caused by Colibacilli, Rotavirus and Coronavirus

Abstract

The major economic importance of neonatal infectious diarrhoeas in calves have justified for a few years the development of control programmes combining both sanitary and medical aspects [7]. The importance of immunity conferred through colostrum and milk has been demonstrated [1] [2] [8]. The vaccination of pregnant cows revealed, in the field, as the most efficient mean to reach a high colostrum and milk immunity [3] [4] [5] [10]. The etiology of neonatal infectious diarrhoeas in cattle is now well-determined different types of colibacilli having well-characterized attachment or virulence factors are now isolated; viruses, rotavirus and coronavirus, have also been evidenced [6] [9] [11] [12].

The authors present the results obtained during a controlled clinical trial by using an inactivated vaccine, adjuvanted with aluminium hydroxyde and saponin. This vaccine is indicated for vaccination of pregnant cows.