Pharmacokinetics of Penicillin-G in Pregnant and Non-Pregnant Ewes and Cows

Authors

  • B. Bengtsson Department of Cattle and Sheep Diseases, Swedish University of Agricultural Sciences, Box 7019, S-750 07 Uppsala, Sweden.
  • S. -O. Jacobsson Department of Cattle and Sheep Diseases, Swedish University of Agricultural Sciences, Box 7019, S-750 07 Uppsala, Sweden.
  • J. Luthman Department of Cattle and Sheep Diseases, Swedish University of Agricultural Sciences, Box 7019, S-750 07 Uppsala, Sweden.

DOI:

https://doi.org/10.21423/aabppro19926660

Keywords:

Penicillin-G, antibacterial agent, pharmacokinetics, pregnant, non-pregnant

Abstract

Penicillin-G (Pen-G) is an antibacterial agent widely used in treating bacterial infections in ruminants. The pharmacokinetics of the drug in cattle and sheep have been studied (1,2,3,4,5) but if pharmacokinetics are affected by pregnancy has to our knowledge not been investigated. The objective of the present study was to compare pharmacokinetics of Pen-G in pregnant and non-pregnant cows and ewes.

Cover image of the Third Volume of the 25th Conference Proceedings: An earl-morning photo of farmland. A small farm is nestled among rolling hills, fields stretching across a curving road that disappears between dark green trees. The barn is a cheery red color with a tin roof. Beneath the photo is the a statement of the conference's theme in white italics: Challenges of the Bovine Industry in the Twenty-First Century. Deep red background.

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Published

1992-08-31

Issue

1992: Volume 3

Section

Mastitis