Assessing Vaccine Efficacy in the Feedlot
DOI:
https://doi.org/10.21423/aabppro19916737Keywords:
bovine practitioner, bacterin, toxoid, vaccine, bovine respiratory disease, Haemophilus somnus bacterin, BRDAbstract
How can you decide which vaccines to recommend to your feedlot clients? The purpose of this presentation is to develop a framework for the bovine practitioner for assessing the value of a commercial bacterin, toxoid, or vaccine by examining the scientific literature. A logical approach to reading this literature would help differentiate published trials that could help you in practice from useless or entirely misleading trials. The principles are also extremely useful for carrying out trials within feedlots in your own practice.
To demonstrate, I will refer generally to bovine respiratory disease (BRD) vaccines, and more specifically to recent research examining the effectiveness of a particular commercial Haemophilus somnus bacterin. Determining the effectiveness of this bacterin could be difficult because the organism is associated with a variety of clinical diseases, referred to generally as hemophilosis,1 and it has been implicated as one of the potential initiators of the BRD complex.2,3 How do you decide whether to recommend the use of this bacterin, or any other vaccine, for the prevention of hemophilosis or BRD?