Bovine Pneumonic Pasteurellosis

A Biotechnological Approach to Control

Authors

  • B. N. Wilkie Department of Veterinary Microbiology and Immunology, Ontario Veterinary College, The University of Guelph, Guelph, Ontario, Canada N1G 2W1
  • P. E. Shewen Department of Veterinary Microbiology and Immunology, Ontario Veterinary College, The University of Guelph, Guelph, Ontario, Canada N1G 2W1

DOI:

https://doi.org/10.21423/aabppro19887007

Keywords:

vaccination, livestock industry, vaccine design, vaccination program, immune response

Abstract

The acknowledged efficacy of vaccination in preventing major infectious diseases is based upon obvious successes such as that against smallpox, which was declared eradicated in 1980 (24), or the Clostridium sp bacterin-toxoids which are used in man and animals.

Expectations for vaccine usefulness are consequently high, but many diseases which are apparently amenable to vaccine-based control remain as significant sources of economic loss in the livestock industry. Failure to observe certain basic principles of vaccine design may have contributed to this. Vaccination is feasible and warranted if directed towards an economically important infectious disease of livestock which is caused by an identified infectious agent with known virulence-mediating determinants which induce protective immune response against a realistic challenge under usual husbandry conditions. The vaccination program must be cost-effective.

Cover image of the Proceedings of the 21st Annual Convention: Cover image is a photo of cattle grazing alongside a river with pine trees and a mountain range in the background. Journal title is written in the upper left corner and conference information in the lower right.

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Published

1988-09-28

Issue

1988

Section

General Session III