Factors Involved in Adverse Reactions to Bovine Biologicals

Abstract

Several bovine biologicals, while generally safe, occasionally are associated with adverse reactions . Vaccines have directly or indirectly induced diseases either by causing the disease they were intended to prevent or making the animal more susceptible to other infection. Biologicals can also induce anaphylaxis or hypersensitivities. Injection site reactions such as abscesses, swellings or granulomas can be directly or indirectly caused by bacterins or vaccines. Other conditions have also been related to use of biologicals.