Whole blood RNA-Seq analysis of stocker calves reveals insights into BRD

Authors

  • M. A. Scott Department of Pathobiology and Population Medicine, Mississippi State University College of Veterinary Medicine, Mississippi State, MS 39762
  • A. R. Woolums Department of Pathobiology and Population Medicine, Mississippi State University College of Veterinary Medicine, Mississippi State, MS 39762
  • C. E. Swiderski Department of Clinical Sciences, Mississippi State University College of Veterinary Medicine, Mississippi State, MS 39762
  • A. D. Perkins Department of Computer Science and Engineering Mississippi State University, Mississippi State, MS 39762
  • B. Nanduri Department of Basic Sciences, Mississippi State University College of Veterinary Medicine, Mississippi State, MS 39762
  • D. R. Smith Department of Pathobiology and Population Medicine, Mississippi State University College of Veterinary Medicine, Mississippi State, MS 39762
  • B. B. Karisch Department of Animal and Dairy Sciences, Mississippi State University, Mississippi State, MS 39762
  • W. B. Epperson Department of Pathobiology and Population Medicine, Mississippi State University College of Veterinary Medicine, Mississippi State, MS 39762

DOI:

https://doi.org/10.21423/aabppro20197213

Keywords:

Bovine respiratory disease, BRD, stocker calves, altered transcriptional profiles

Abstract

Bovine respiratory disease (BRD) is the leading cause of morbidity and mortality in stocker cattle. It is difficult to predict which cattle will develop BRD. Improved prediction could facilitate more responsible and rational use of antimicrobials and vaccines to limit BRD. We hypothesize that altered transcriptional profiles in the blood of stocker calves on arrival represent regulatory pathways including biomarkers useful to improve prediction of BRD risk.

Cover image of the 52nd Conference Proceedings: A photo of a herd of cattle shot from below. A black and white cow is looking curiously at the phototgrapher. Yellow

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Published

2019-09-12

Issue

2019

Section

Research Summaries

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