High NEFA concentration in postpartum dairy cows is not strongly correlated with hyperketonemia

are there associated genomic regions?

Authors

  • F. A. Leal Yepes College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853
  • S. Mann College of Veterinary Medicine, Cornell University, Ithaca, NY 14853
  • J. A. A. McArt College of Veterinary Medicine, Cornell University, Ithaca, NY 14853
  • H. J. Huson College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853
  • T. R. Overton College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853
  • D. V. Nydam College of Veterinary Medicine, Cornell University, Ithaca, NY 14853

Keywords:

early postpartum, negative energy balance, NEB, dairy cattle, non-esterified fatty acids, NEFA, ketone, hyperketonemia

Abstract

Early postpartum dairy cows are subject to physiological changes, including adaptations to support rapidly increasing energy output in milk in excess of energy intake. During this period of negative energy balance (NEB), cows respond by mobilizing lipid and protein reserves in order to support lactation and vital functions. Fat reserves are mobilized as non-esterified fatty acids (NEFA) that can be extracted by the liver and either oxidized or re-esterified, then exported as very low density lipoproteins or accumulated in the liver tissue. Cows vary in their success in supporting these physiological functions during NEB. Some cows adapt very well to NEB; however, other cows do not, resulting in excessive ketone body synthesis.

Cover image of the 47th Conference Proceedings: An image of a herd of cattle in a field at dusk. Three cows are standing in the foreground, looking adorable. Yellow background.

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Published

2014-09-18

Issue

2014

Section

Research Summaries 2

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