Tulathromycin metaphylaxis increases prevalence of multidrug resistant Mannheimia haemolytica while improving health in stocker calves

Authors

  • W. B. Crosby Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, 39762
  • B. B. Karisch Department of Animal and Dairy Sciences, College of Agriculture and Life Sciences, Mississippi State University, Mississippi State, MS, 39762
  • L. M. Hiott Bacterial Epidemiology & Antimicrobial Resistance Research, U.S. National Poultry Research Center,USDA-ARS, Athens, GA, 30605
  • J. D. Loy Nebraska Veterinary Diagnostic Center, School of Veterinary Medicine and Biomedical Sciences, University of Nebraska, Lincoln, NE, 68583
  • W. B. Epperson Department of Pathobiology and Population Medicine, Mississippi State University, Mississippi State, MS 39762
  • S. F. Capik Texas A&M AgriLife Research, Texas A&M University System, Amarillo, TX, 79119
  • P. S. Morley Texas A&M AgriLife Research, Texas A&M University System, Amarillo, TX, 79119
  • A. R. Woolums Department of Pathobiology and Population Medicine, Mississippi State University, Mississippi State, MS 39762

DOI:

https://doi.org/10.21423/aabppro20228647

Abstract

Bovine respiratory disease (BRD) is commonly controlled by metaphylaxis, but increasing prevalence of antimicrobial re­sistant (AMR) Mannheimia haemolytica (MH) may decrease ef­ficacy. The objective of this study was to determine the effect of macrolide metaphylaxis on 1) morbidity and mortality in stocker cattle over a 21-day period and 2) isolation rate and anti­microbial susceptibility of MH at arrival (d0) and d21.

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Published

2023-07-17

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