Pharmacokinetics and pharmacodynamics of pantoprazole in calves

Authors

  • J. Olivarez Biomedical Sciences, Iowa State University, Ames, IA 50010
  • P. Mulon Large Animal Clinical Sciences, University of Tennessee, Knoxville, TN 37996
  • J. Smith Biomedical Sciences, Iowa State University, Ames, IA 50010
  • H. Cremerius Large Animal Clinical Sciences, University of Tennessee, Knoxville, TN 37996
  • C. Cantrell Large Animal Clinical Sciences, University of Tennessee, Knoxville, TN 37996
  • A. Kreuder Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011
  • L. Ebner Biomedical and Diagnostic Sciences, University of Tennessee, Knoxville, TN 37996
  • S. Cox Biomedical and Diagnostic Sciences, University of Tennessee, Knoxville, TN 37996

DOI:

https://doi.org/10.21423/aabppro20228691

Abstract

Abomasal ulcers occur commonly in veal calves as well as and hospitalized beef calves. One of the recognized therapeutic in­terventions for abomasal and gastric ulceration is the increase of the gastric pH. The lack of efficacy data for gastroprotec­tants, such as pantoprazole, for ulcer prevention and treatment in cattle is a health and welfare issue. The goal of this study was to investigate the pharmacokinetics and pharmacodynamics of pantoprazole administered to healthy calves.

Downloads

Published

2023-07-17

Issue

No. 55 (2022): 2022 Annual Conference Proceedings

Section

Research Summaries