A randomized non-inferiority study evaluating the efficacy of two commercially available teat sealants in dairy cows

Authors

  • M. P. Buckley Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011
  • J. Bayne Auburn University, College of Veterinary Medicine, Auburn, AL 36849
  • G. S. Silva Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA 50011
  • T. Tomazi Dairy Technical Services, Merck Animal Health, Kenilworth, NJ 07033
  • B. E. Miller Dairy Technical Services, Merck Animal Health, Kenilworth, NJ 07033
  • S. M. Godden Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108
  • P. J. Gorden Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA 50011

DOI:

https://doi.org/10.21423/aabppro20228699

Abstract

The primary objective of this study was to compare the effi­cacy of a new internal teat sealant (ShutOutTM, Merck Animal Health, Madison, NJ) (SO) to the current U.S. industry leader (Orbeseal®, Zoetis, Parsippany, NJ) (ORB). This comparison was based on a non-inferiority evaluation of quarter-level new in­fection risk during the dry period, with secondary comparisons of cure risk, incidence of clinical mastitis at the cow level dur­ing the first 120 days in milk, as well as cow-level performance in early lactation based on milk production, somatic cell count (SCC), and risk for removal from the herd.

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Published

2023-07-17

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