Characterizing the influence of various antimicrobials used for metaphylaxis against bovine respiratory disease on host transcriptome responses

Authors

  • R. Bigelow Department of Agricultural Sciences, West Texas A&M University, Canyon, TX 79016
  • J. Richeson Department of Agricultural Sciences, West Texas A&M University, Canyon, TX 79016
  • M. McClurg Veterinary, Education, Research, and Outreach Center, Texas A&M University, Canyon, TX 79015
  • P. Morley Veterinary, Education, Research, and Outreach Center, Texas A&M University, Canyon, TX 79015
  • R. Valeris-Chacin Veterinary, Education, Research, and Outreach Center, Texas A&M University, Canyon, TX 79015
  • M. Scott Veterinary, Education, Research, and Outreach Center, Texas A&M University, Canyon, TX 79015

DOI:

https://doi.org/10.21423/aabppro20238901

Abstract

Bovine respiratory disease (BRD) is a multifactorial disease complex resulting from interactions among host immunologi­cal response, environmental conditions and polymicrobial components. Metaphylaxis, or the mass administration of an antimicrobial upon arrival to a stocker or feedlot facility, is the primary method of control for BRD. Our objective was to deter­mine the influence of 6 different antimicrobials used metaphy­lactically on the whole blood host transcriptome in healthy steers upon and following arrival to the feedlot.

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Published

2024-05-10

Issue

No. 56 (2023): 2023 Annual Conference Proceedings

Section

Research Summaries

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