Comparison of Salmonella Dublin SRP vaccination programs on the development of immunity in calves

Abstract

Salmonella Dublin is a common cause of calf illness and is en­demic in many regions of the U.S. dairy industry. A 2016 report from the National Veterinary Services Lab found S. Dublin was the most commonly isolated Salmonella serotype obtained from ill cattle in the U.S. This serotype is also considered to be host-adapted in bovine and therefore carrier animals that appear normal can be shedders and a source for maintaining the infec­tion within a herd. As such, finding mechanisms to protect naïve animals from clinical disease can reduce losses in dairy herds. The objective of this work was to describe the immune response stimulated by experimental Salmonella Dublin SRP vaccines.