Effects of injectable trace minerals on the inflammatory cytokines’ response to vaccination in dairy calves

Authors

  • A. Megahed Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida
  • W. Filho Carvalho Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida
  • A. Stoskute Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA 30602
  • R. Palomares Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida
  • J. Bittar Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida

DOI:

https://doi.org/10.21423/aabppro20238929

Abstract

Trace mineral supplementation concurrent with the bovine respiratory diseases complex (BRDC) vaccine boosts antibody production and leukocyte proliferation. However, the mecha­nism underlying this effect is not well understood. On the other hand, cytokines response post-vaccination is an important driver of both humoral and cellular immunity. Therefore, we hypothesized that trace mineral supplementation may improve BRD vaccine immunogenicity and effectiveness by modulating inflammatory cytokines in dairy calves. Our objective was to characterize the effects of injectable trace minerals (ITM) on the cytokines response to the BRD modified-live virus (MLV) vaccine in post-weaning dairy calves.

Downloads

Published

2024-05-10

Issue

No. 56 (2023): 2023 Annual Conference Proceedings

Section

Research Summaries