A randomized clinical trial assessing the use of a single injection of dexamethasone combined with oral propylene glycol therapy for the treatment of hyperketonemia

Authors

  • E. Tatone Department of Population Medicine, University of Guelph, Guelph, N1G 2W1, Canada
  • M. Capel Perry Veterinary Services, Perry, NY 14530
  • J. Gordon Department of Population Medicine, University of Guelph, Guelph, N1G 2W1, Canada
  • S. LeBlanc Department of Population Medicine, University of Guelph, Guelph, N1G 2W1, Canada
  • T. Duffield Department of Population Medicine, University of Guelph, Guelph, N1G 2W1, Canada

DOI:

https://doi.org/10.21423/aabppro20153590

Keywords:

hyperketonemia, dairy cattle, BHBA

Abstract

The treatment of hyperketonemia (HK, blood β-hydroxybutyrate (BHBA) > 1.2 mmol/L) with oral propylene glycol has proven benefits. Parenteral administration of glucocorticoids has been suggested as an adjunctive therapy; however it has not been assessed in a randomized controlled trial. The objective of this research was to evaluate the effect on the probability of cure, risk of subsequent disease, and milk production of a 1-time intramuscular injection of dexamethasone as an adjunctive therapy for HK.

Cover image of the 48th Conference Proceedings: An image of Dr. Fred Gingrich II dressed in a red shirt and overalls and standing in front of dairy cows in a barn interior. Yellow background.

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Published

2015-09-17

Issue

2015

Section

Research Summaries 2

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