Impact of passive immunity induced by maternal vaccination on subsequent immunization and disease-sparing in early-weaned beef calves challenged with highly virulent BVDV

Authors

  • P. H. Walz Department ofPathohiology, Auburn University, Auburn, AL 36849
  • A. R. Richeson Department ofPathohiology, Auburn University, Auburn, AL 36849
  • K. P. Riddell Department ofPathohiology, Auburn University, Auburn, AL 36849
  • M. D. Givens Department ofPathohiology, Auburn University, Auburn, AL 36849
  • M. F. Chamorro Department of Clinical Sciences, Auburn University, Auburn, AL 36849
  • A. V. Santen Department ofAgronomy and Soil Sciences, Auburn University, Auburn, AL 36849

DOI:

https://doi.org/10.21423/aabppro20153620

Keywords:

vaccination, bovine viral diarrhea virus, BVDV, passively-derived antibody, early weaned, calves, beef cattle

Abstract

Vaccination programs have been developed to limit disease associated with bovine viral diarrhea virus (BVDV) infection. The ultimate goal of BVDV vaccination is to induce immunity that prevents viral replication after infection; however, passively acquired BVDV-specific neutralizing antibodies can impact immunity and vaccine responses in the young calf. The purpose of this study was to examine the impact of passively-derived antibody on vaccine response and mitigation of disease in early weaned beef calves whose passive immune status was documented, and when vaccination and challenge were separated by only 5 days.

Cover image of the 48th Conference Proceedings: An image of Dr. Fred Gingrich II dressed in a red shirt and overalls and standing in front of dairy cows in a barn interior. Yellow background.

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Published

2015-09-17

Issue

2015

Section

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