Evaluation of Pasteurella and Haemophilus Vaccines

Authors

  • Anthony W. Confer Department of Veterinary Pathology, Department of Veterinary Parasitology, Microbiology and Public Health, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078
  • Robert W. Fulton Department of Veterinary Pathology, Department of Veterinary Parasitology, Microbiology and Public Health, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078

DOI:

https://doi.org/10.21423/aabppro19946234

Keywords:

experimental studies, vaccines, H. somnus, P. multocida, P. haemolytica, antigens, immunity, Mechanisms of immunity

Abstract

The family Pasteurellaceae Pohl contains gramnegative, facultatively anaerobic and fermentative bacteria of the genera Pasteurella, Haemophilus, and Actinobacillus. Of these genera, Haemophilus somnus, Pasteurella multocida and Pasteurella haemolytica are prominent pathogens in domestic cattle causing severe diseases and major economic losses. Mechanisms of immunity to these bacteria have been difficult to determine, and efficacious vaccines have been a challenge to develop and evaluate.

In this review, we will summarize current published data on antigens and immunity associated with H. somnus, P. multocida, and P. haemolytica. This will be followed by a discussion of experimental studies conducted in our laboratories using commercial P. haemolytica vaccines.

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Published

1994-09-22

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