BVD
What's the Latest
DOI:
https://doi.org/10.21423/aabppro19926511Keywords:
Bovine viral diarrhea virus, BVDV, mucosal disease, biotypesAbstract
Bovine viral diarrhea virus (BVDV) is an ubiquitous viral pathogen of cattle that induces disease involving the respiratory, enteric,
reproductive, lymphoid, and nervous systems. The diseases commonly associated with BVDV infections are termed acute BVD, mucosal disease, and chronic BVD. In North America, BVDV is a leading cause of economic loss in beef and dairy cattle. Two biotypes of BVDV exist, and these have cytopathic or noncytopathic characteristics in cell culture. The cytopathic virus kills susceptible cell cultures and the noncytopathic virus has little effect on cultured cells. However, there is no correlation between the effects of virus in cell culture and the effects in cattle. Certain noncytopathic BVDV are extremely virulent and kill adult cattle. Conversely, many cytopathic BVDV induce only mild disease in cattle.