Serum amyloid A concentration as an inflammatory marker in endotoxemic model calves

Abstract

Serum amyloid A (SAA) is an acute phase protein that increases in concentration in the serum in the early stages of inflammation. SAA is used to diagnose inflammatory diseases in humans, cats, and horses. Such an inflammatory marker to diagnose inflammatory diseases needs to be investigated in cattle. Furthermore, the relationship between systemic inflammation and serum SAA concentrations needs to be examined in order to improve food animal health care. However, no studies have been reported on the sequential change in SAA in cattle with endotoxemia. Therefore, the aim of the present study was to examine serum SAA concentrations in cattle with systemic inflammation caused by endotoxin.