Serum amyloid A assay using a new reagent is the most useful in the diagnose of mastitis

Abstract

Serum amyloid A (SAA) is an acute phase protein (APP) that increases in concentration in the serum in the early stages of inflammation. There are many studies have concluded that SAA is useful to diagnose inflammatory diseases in cattle. However, the SAA assay using an automated latex agglutination turbidimetric immunoassay for human was less accurate in cattle. Accordingly, the new SAA assay for cattle has developed. The aim of the present study was to clarify usefulness of new reagent and to evaluate its diagnostic ability in comparison to other APPs, such as C-reactive protein (CRP), haptoglobin (HPT) and α1-acid glycoprotein (AGP).