Assessment of systemic inflammation following oral calcium supplementation in postpartum dairy cows – a pilot-scale randomized controlled trial

Authors

  • R. Couto Serrenho Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
  • E. Morrison Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
  • T. C. Bruinje Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
  • S. J. LeBlanc Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, N1G 2W1, Canada

DOI:

https://doi.org/10.21423/aabppro20228651

Abstract

A new line of thinking is emerging to link inflammation with calcium metabolism. Around parturition, dairy cows inevitably and perhaps necessarily experience some degree of systemic inflammation, but excessive or dysregulated inflammation likely contributes to inflammatory disease. Immune activa­tion decreases blood Ca, so greater extracellular Ca availability may potentiate or sustain inflammation. Hypocalcemia may be an adaptive response to inflammation. The objective of this study was to investigate a possible role of supplemental calcium (Ca) in postpartum systemic inflammation in dairy cows. We hypothesized that in clinically healthy multiparous cows, post­partum administration of supplemental Ca may increase serum concentrations of markers of inflammation.

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Published

2023-07-17

Issue

No. 55 (2022): 2022 Annual Conference Proceedings

Section

Research Summaries

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