Time-course RNA-Seq analysis defines immunological and inflammatory mechanisms influenced by bovine respiratory disease

Authors

  • M. A. Scott Veterinary Education, Research and Outreach Center, Texas A&M University and West Texas A&M University, Canyon, TX 79015
  • A. R. Woolums Department of Pathobiology and Population Medicine, Mississippi State University, Mississippi State, MS 39762
  • A. C. Thompson Department of Pathobiology and Population Medicine, Mississippi State University, Mississippi State, MS 39762
  • B. B. Karisch Department of Animal and Dairy Sciences, College of Agriculture and Life Sciences, Mississippi State University, Mississippi State, MS, 39762

DOI:

https://doi.org/10.21423/aabppro20228657

Abstract

Bovine respiratory disease (BRD) remains the leading disease in beef cattle. Host gene expression at facility arrival may indi­cate BRD risk, however, time-course RNA-Seq could define how BRD development influences immunological and inflammatory responses. Here, we evaluated blood transcriptomes of high-risk beef cattle at 3 timepoints to illustrate BRD-associated host response.

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Published

2023-07-17