Leukocyte dynamics in vaccinated and unvaccinated animals following dual challenge with Bovine Viral Diarrhea Virus-Mannheimia haemolytica model to compare vaccine efficacy in calves

Authors

  • S. Perkins-Oines RTI, LLC, Brookings, SD 57006
  • S. Van Holland RTI, LLC, Brookings, SD 57006
  • K. Abdelsalam RTI, LLC, Brookings, SD 57006
  • N. Bate Applied Animal Diagnostics, Morrisville, NC 27560
  • J. Drach Applied Animal Diagnostics, Morrisville, NC 27560
  • C. Chase Department of Veterinary and Biomedical Sciences, South Dakota State University

DOI:

https://doi.org/10.21423/aabppro20238919

Abstract

Bovine respiratory disease continues to be the greatest threat to calf health. One of the common recommendations is to vaccinate young beef and dairy calves at 30-60 days of age to provide protection at weaning or when commingled. The study objective was to determine whether there were any dif­ferential leukocyte changes that could be measured following a dual challenge with Bovine Viral Diarrhea Virus (BVDV) and M. haemolytica ~5 months after vaccination.

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Published

2024-05-10