In vitro efficacy of anti-protozoal compounds as a novel treatment for Tritrichomonas foetus in bulls

Authors

  • J. H. Koziol Department of Clinical Sciences, Auburn University, Auburn, Alabama 36849
  • D. F. Wolfe Department of Clinical Sciences, Auburn University, Auburn, Alabama 36849
  • M. A. Edmondson Department of Clinical Sciences, Auburn University, Auburn, Alabama 36849
  • S. H. Duran Department of Clinical Sciences, Auburn University, Auburn, Alabama 36849
  • T. Passler
  • J. A. Gard Department of Clinical Sciences, Auburn University, Auburn, Alabama 36849

DOI:

https://doi.org/10.21423/aabppro20163432

Abstract

Currently, there are no legal treatments in the United States for cattle infected with Tritrichomonas foetus. This obligate parasite of the reproductive tract of the bovid creates serious economic loss in the cattle industry in the United States. The hypothesis of this study was that benzimidazoles (oxibendazole or oxfendazole) or ponazuril combined with a polymer enhancer, specifically polymer lecithin organogel (PLO), in a topical formulation may be an effective treatment for bulls infected with r foetus. Three in vitro experiments were performed to evaluate the antiprotozoal effects of the benzimidazole and ponazuril formulations, and all involved components on the growth of r foetus organisms.

Cover image of the 49th Conference Proceedings: An image of a herd of Angus cattle grazing in a field at dusk. Yellow background.

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Published

2016-09-15

Issue

2016

Section

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