The effect of anti-Il-10 IgY on health and performance of preweaned dairy calves

a dose response study

Authors

  • S. Raabis Department of Medical Sciences, University of Wisconsin-Madison School of Veterinary Medicine, Madison, WI 53706
  • S. McGuirk Department of Medical Sciences, University of Wisconsin-Madison School of Veterinary Medicine, Madison, WI 53706
  • M. Cook Department of Animal Sciences, University of Wisconsin-Madison School of Veterinary Medicine, Madison, WI 53706
  • J. Sand Department of Animal Sciences, University of Wisconsin-Madison School of Veterinary Medicine, Madison, WI 53706
  • J. Rieman Department of Medical Sciences, University of Wisconsin-Madison School of Veterinary Medicine, Madison, WI 53706
  • K. Rottenberg Department of Medical Sciences, University of Wisconsin-Madison School of Veterinary Medicine, Madison, WI 53706
  • T. Ollivett Department of Medical Sciences, University of Wisconsin-Madison School of Veterinary Medicine, Madison, WI 53706

DOI:

https://doi.org/10.21423/aabppro20163461

Abstract

Cryptosporidium parvum infection is a nearly ubiquitous infection in dairy herds for which there are no approved treatments or vaccines available in the US. Therefore, oral administration of immunoglobulins to control enteric disease in calves is of significant interest. Antibodies survive gastrointestinal transit, are accessible in the intestinal lumen, and remain locally active without the risk of violative residues. Our research team previously demonstrated that calves fed anti-11-10 IgY in milk had higher fecal pH, reduced respiratory disease, and increased frame measurements. Therefore, the objective of the current study was to carry out a dose-response trial evaluating the effects of feeding 0.5x, 2.0x, and lx the dose from the original study on respiratory and gastrointestinal health, C. parvum oocyst shedding, and calf growth.

Cover image of the 49th Conference Proceedings: An image of a herd of Angus cattle grazing in a field at dusk. Yellow background.

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Published

2018-02-09

Issue

2016

Section

Research Summaries 2