Altered plasma pharmacokinetics of ceftiofur hydrochloride in cows affected with severe clinical mastitis

Authors

  • P. J. Gorden Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA 50011
  • M. D. Kleinhenz Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA 50011
  • L. W. Wulf Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA 50011
  • B. KuKanich Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506
  • C. Wang Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA 50011
  • J. F. Coetzee Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA 50011

DOI:

https://doi.org/10.21423/aabppro20153540

Keywords:

Mastitis, dairy cows, CEF

Abstract

Our hypothesis is that cows affected with severe infectious disease will have altered CEF PK relative to healthy cows, necessitating variance in dose regimens and withdrawal periods.

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Published

2015-09-17

Issue

Section

Research Summaries 4