Particle-induced x-ray emission analysis of trace and major elements in serum of acute coliform mastitis in cattle

Abstract

Acute coliform mastitis (ACM) is 1 of the most frequent causes culling dairy cattle. This condition is typically associated with local inflammation and systemic inflammatory responses as a result of local responses to inflammation. Interleukin-6, interleukin-1, and tumor necrosis factor-alpha play central roles in the production of acute phase responses associated with inflammation and are well characterized. However, knowledge about the biological significance of alterations in trace and major elements associated with production of cytokines during the immune response is limited. Thus, the aim of this study was to investigate the concentrations and relationships between trace and major elements in serum from dairy cattle with acute coliform mastitis. Receiver operating characteristic (ROC) curves were used to describe the performance of serum in screening for acute coliform mastitis and to propose diagnostic cutoffs for cattle. Further, this data may provide further understanding of trace and major minerals associated clinically with coliform mastitis.