Periparturient Effects of Feeding a Low Dietary Cation-Anion Difference Diet on the Metabolism of High-Producing Dairy Cows
DOI:
https://doi.org/10.21423/aabppro20094318Keywords:
protein metabolism, metabolic acidosis, phosphorus homeostasis, insulin responsiveness, insulin sensitivity, dietary cation-anion difference, periparturient hypocalcemiaAbstract
Feeding rations with low dietary cation-anion difference (DCAD) to dairy cows during late gestation is a commonly used strategy in large herds to prevent periparturient hypocalcemia. Although the efficacy of low DCAD rations in reducing the incidence of clinical hypocalcemia is well documented, it is not clear whether the ensuing metabolic acidosis is associated with deleterious side effects during the transition period. The objective of the study presented here was to determine the effect of fully compensated metabolic acidosis on calcium and phosphorus homeostasis, insulin responsiveness, and insulin sensitivity as well as on indices for protein metabolism.