The Evaluation of Danofloxacin in the Therapy of Pneumonia Associated With Pasteurella Species in Young Calves

A Summary

Authors

  • H. Barthel Animal Health Division, Pfizer, Inc, Karlsruhe, Germany
  • C. J. Giles Central Research Division, Pfizer, Inc, Sandwich, U.K.
  • B. Roelants Animal Health Division, Pfizer, Inc, Brussels, Belgium
  • D. Stellingwerf Animal Health Division, Pfizer, Inc, Rotterdam, Netherlands
  • C. Thomasson European Clinical Development, Pfizer, Inc, Orsay, France
  • S. T. Tolling Animal Health Group, Pfizer, Inc, New York, U.S.A.

DOI:

https://doi.org/10.21423/aabppro19926436

Keywords:

Acute pneumoni, Pasteurella spp., lung lesions, management factors, fluoroquinolone antimicrobial danofloxacin

Abstract

Acute pneumonia is an economically important disease afflicting young cattle world-wide. The disease develops as a complex interaction and the aetiology of any outbreak is often multifactorial (1). Pasteurella spp. are the most important bacteria involved causing fibrinous bronchopneumonia (2, 3), but more frequently they increase the severity of lung lesions inflicted by viruses and/or mycoplasmas. Transport, housing and mixing of animals are management factors contributing to outbreaks of acute pneumonia. This paper summarizes the results of seven studies conducted in Europe in which the efficacy of the fluoroquinolone antimicrobial danofloxacin* against naturally occurring outbreaks of acute pneumonia in calves was evaluated in comparison with trimethoprim/sulpha.

Cover image of the First Volume of the 25th Conference Proceedings: An earl-morning photo of farmland. A small farm is nestled among rolling hills, fields stretching across a curving road that disappears between dark green trees. The barn is a cheery red color with a tin roof. Beneath the photo is the a statement of the conference's theme in white italics: Challenges of the Bovine Industry in the Twenty-First Century. Deep red background.

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Published

1992-08-31

Issue

1992: Volume 1

Section

Respiratory Disease