Assessing the Epidemiologic Impact of Vaccination for Bovine Viral Diarrhea Virus

Authors

  • S. P. Rodning Department of Animal Sciences, Auburn University, Auburn, AL
  • M. D. Givens Department of Pathobiology, Auburn University, Auburn, AL
  • Y. Zhang Animal Health Research, Auburn University, Auburn, AL
  • M. S. D. Marley Department of Pathobiology, Auburn University, Auburn, AL
  • C. L. Nunley Department of Animal Sciences, Auburn University, Auburn, AL
  • P. H. Walz Department of Pathobiology, Auburn University, Auburn, AL

DOI:

https://doi.org/10.21423/aabppro20084466

Keywords:

BVDV vaccines, persistently infected, bovine viral diarrhea virus

Abstract

Currently, to validate efficacy of BVDV vaccines, clinical trials commonly involve challenge of vaccinates with a single intranasal inoculation of a BVDV field strain. Licensed vaccines provide nearly complete protection (91 to 100%) of dams and developing fetuses after this artificial challenge. However, exposure to animals persistently infected (PI) with BVDV may better represent viral challenge under field conditions. The objective of this research is to assess the efficacy of vaccination for control of bovine viral diarrhea virus (BVDV).

Cover image of the 41st Conference Proceedings: A herd of cattle standing in the field, framed by a cloudy sky. Yellow background.

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Published

2008-09-25

Issue

2008

Section

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