Determination of alpha-toxin antibodies against Staphylococcus aureus and phagocytic ability postimmunization in rabbits

Authors

  • Hong Ryul Han College of Veterinary Medicine, Seoul National University, Republic of Korea
  • Hee Myung Park College of Veterinary Medicine, Seoul National University, Republic of Korea
  • Doo Kim College of Veterinary Medicine, Kangwon National University, Republic of Korea

DOI:

https://doi.org/10.21423/bovine-vol1998no32.1p14-16

Keywords:

antibodies, bacterial diseases, bovine mastitis, disease prevention, mastitis, phagocytosis, toxins, vaccination, vaccines

Abstract

30 rabbits were inoculated i.m. 3 times, at 2-week intervals, with a S. aureus subunit bacterin preparation (10 HU of alpha-toxin, 600 æg of capsular polysaccharide, 200 æg of fibronectin binding protein). The levels of specific antibodies against alpha toxin in immunized rabbits were significantly increased over 4 weeks compared with control rabbits, which showed no response. There was no significant difference between immunized and control rabbits in bacterial clearance rate. The use of the vaccine for prevention of bovine mastitis is discussed.

Cover image of Volume 32.1 of the Bovine Practitioner: a copy of the painting "Summer Scenes" by Bonnie Mohr which depicts a herd of cattle standing in a field with a dramatic skyscape in the background. The lighting is very warm and many of the cows gaze placidly at the viewer.

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Published

1998-01-01

Issue

No. 32.1 (1998 January)

Section

Articles

How to Cite

Determination of alpha-toxin antibodies against Staphylococcus aureus and phagocytic ability postimmunization in rabbits. (1998). The Bovine Practitioner, 1998(32.1), 14-16. https://doi.org/10.21423/bovine-vol1998no32.1p14-16