Clinical efficacy of enrofloxacin against bovine respiratory disease comparing different treatment regimens

Authors

  • M. Hamm Bayer Animal Health, Clinical Development, D-51368 Leverkusen, Germany
  • T. Wollen Bayer Animal Health, Clinical Development, Box 390, Shawnee, KS 66201, USA
  • R. Highland Bayer Animal Health, Clinical Development, Box 390, Shawnee, KS 66201, USA
  • J. Davidson Health Management Services, Box 2046, Tulare, CA 93275, USA
  • T. TerHune Health Management Services, Box 2046, Tulare, CA 93275, USA
  • K. Lechtenberg Midwest Veterinary Services, Box 49, Oakland, NE 68045, USA
  • M. Apley Veterinary Research and Consulting Services, 5626 W. 19th Street, Greely, CO 80634, USA
  • D. Miles Veterinary Research and Consulting Services, 5626 W. 19th Street, Greely, CO 80634, USA
  • M. Wray Veterinary Research and Consulting Services, 5626 W. 19th Street, Greely, CO 80634, USA
  • D. Bechtol Agri Research Center, Box 37, Canyon, TX 79015, USA
  • A. Waite Agri Research Center, Box 37, Canyon, TX 79015, USA
  • E. Johnson Johnson Research, RT. 1, Box 1142, 24007 Hwy #20/26, Parma, ID 83660, USA
  • P. Scott University of of Edinburgh, Large Animal Practice, Easter Bush, Roslin, Midlothian, EH25 9RG
  • D. Copeland Bayer Animal Health, Clinical Development, Box 390, Shawnee, KS 66201, USA

DOI:

https://doi.org/10.21423/bovine-vol33no1p56-59

Keywords:

drug therapy, enrofloxacin, respiratory diseases, fluoroquinolone antibiotics, antibiotics

Abstract

Enrofloxacin is being successfully used for the treatment of respiratory disease of cattle in many countries. The established treatment regimen is a daily injection for 3 to 5 days with a dose range from 2.5 - 5.0 mg/kg. A predominant finding is that a single treatment with an higher dose of 7.5 - 12.5 mg/kg shows excellent clinical efficacy under feedlot conditions. The results of several clinical field trials conducted in the USA and Europe during the last years were used to compare the clinical efficacy of the daily and single treatment regimens. The studies were carried out under varied housing and weather conditions. The results show the equivalency of both treatment regimens. Consequently, the usage of enrofloxacin enables veterinarians to utilize their experience and medical expertise to design either a daily or a single treatment regimen according to the specific infection and management situation.

Cover image of Volume 33, No.1 of the Bovine Practitioner, which depicts four different types of bovine practice under the banner "The Journal for All Bovine Practitioners": a photo from a dairy farm provided by Dr. Jim Jarrett of Rome, GA; a photo of a cow-calf practice provided by Dr. Larry Rice of San Antonio, TX; a stocker photo provided by Dr. Bob Smith of Stillwater, OK; and a feedlot photo provided by Mike Hunter of Texas County Feedyard, Guymon, OK

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Published

1999-01-01

How to Cite

Hamm, M., Wollen, T., Highland, R., Davidson, J., TerHune, T., Lechtenberg, K., Apley, M., Miles, D., Wray, M., Bechtol, D., Waite, A., Johnson, E., Scott, P., & Copeland, D. (1999). Clinical efficacy of enrofloxacin against bovine respiratory disease comparing different treatment regimens. The Bovine Practitioner, 33(1), 56–59. https://doi.org/10.21423/bovine-vol33no1p56-59

Issue

Vol. 33, No. 1 (1999 January)

Section

Articles

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