A Comparison of serological responses when modified-live infectious bovine rhinotracheitis virus vaccine and Mannheimia haemolytica bacterin-toxoid are administered with needle-free versus conventional needle-based injection in yearling feedlot steers

Authors

  • Larry C. Hollis Department of Animal Sciences and Industry, Kansas State University, Manhattan, KS 66506
  • John F. Smith Department of Animal Sciences and Industry, Kansas State University, Manhattan, KS 66506
  • Bradley J. Johnson Department of Animal Sciences and Industry, Kansas State University, Manhattan, KS 66506
  • Sanjay Kapil Diagnostic Medicine I Pathobiology, Kansas State University, Manhattan, KS 66506
  • Derek A. Mosier Diagnostic Medicine I Pathobiology, Kansas State University, Manhattan, KS 66506

DOI:

https://doi.org/10.21423/bovine-vol39no2p106-109

Keywords:

bacterial diseases, immune response, immunization, live vaccines, steers, vaccination

Abstract

A total of 111 yearling feedlot steers were vaccinated with 5-way modified-live virus vaccine and Mannheimia haemolytica (MH) bacterin-toxoid, utilizing either needle-free or conventional needle-and-syringe injection techniques. Blood samples were collected from all steers at the time of vaccination and 21 days later, and serum was analyzed for antibody titers to infectious bovine rhinotracheitis (IBR) virus and M. haemolytica (MH) leukotoxin. Serological response to the IBR viral fraction of the 5-way viral vaccine was significantly higher (P=0.001) on day 21 following administration with needle-free injection, compared to conventional needle injection. Serological responses to the MH supernatant and cell-associated antigens were not statistically different (P=0.06) on day 21 following administration with needle-free injection, compared to conventional needle injection.

Cover image of Volume 39, No.2 of the Bovine Practitioner: a photo of the man, presumably Dr. Brett A. Gardner, standing by a feed trough with his hands on his hips surrounded by cattle that might be Black Baldies

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Published

2005-06-01

Issue

Vol. 39, No. 2 (2005 June)

Section

Articles

How to Cite

A Comparison of serological responses when modified-live infectious bovine rhinotracheitis virus vaccine and Mannheimia haemolytica bacterin-toxoid are administered with needle-free versus conventional needle-based injection in yearling feedlot steers. (2005). The Bovine Practitioner, 39(2), 106-109. https://doi.org/10.21423/bovine-vol39no2p106-109