Concentrations and residues of gentamicin in the milk of dairy cows after intramammary infusion

Authors

  • G. Ziv Ministry of Agriculture, Kimron Veterinary Institute, Bet Dagan, Israel

DOI:

https://doi.org/10.21423/bovine-vol1981no16p30-35

Keywords:

antibiotic residues, Antibiotics, bovine mastitis, drug residues, drug therapy, gentamicin, mammary glands, milk, Pharmacokinetics, Pharmacology, residues, aminoglycoside antibiotics, cows

Abstract

Between 50 and 500 mg gentamicin base was infused into certain quarters of 29 cows free from mastitis. Mastitis was induced in two quarters of each of six cows by infusion of Escherichia coli endotoxin, and gentamicin was infused 12 and 36 hours afterwards. Milk concentrations of the antibiotic of 2 mu g/ml or more were maintained for 3-4 milkings providing at least 100 mg was infused. After treatment of inflamed quarters, the antibiotic persisted in milk for 8 milkings after 250 mg and 9 milkings after 500 mg.

Cover image of the 16th Volume of the Bovine Practitioner: a photo of Seattle with Mount Rainier in the background and the Kingdome in the middle distance.

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Published

1981-11-01

Issue

No. 16 (1981 November)

Section

Articles

How to Cite

Concentrations and residues of gentamicin in the milk of dairy cows after intramammary infusion. (1981). The Bovine Practitioner, 1981(16), 30-35. https://doi.org/10.21423/bovine-vol1981no16p30-35