Antibody responses of heifers vaccinated with reduced doses of Brucella abortus strain 19

Authors

  • Anthony W. Confer Department o f Veterinary Pathology, Oklahoma State University, Stillwater, OK 74078
  • Gerald M. Buening Department of Veterinary Microbiology, University of Missouri, Columbia, MO 65211
  • Brian H. Espe Veterinary Extension, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078
  • Robert A. Smith Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078

DOI:

https://doi.org/10.21423/bovine-vol1983no18p174-178

Keywords:

bacterial diseases, brucellosis, Dosage, Immune response, Live vaccines

Abstract

Serum samples were obtained over a six month period from heifers that were either vaccinated with Brucella abortus Strain 19 at one of two reduced doses (109 or 1010 CFU) or not vaccinated. Reactor status was determined by 5 standard tests as well as the hemolysis in gel test (HIGT) and enzyme-linked immunosorbant assay (ELISA). With the standard tests, 50% of the low dose vaccinates and 68% of the higher dose vaccinates were serologically positive 1 month after vaccination. Six months after vaccination, only 8% of the low dose vaccinates and 27% of the higher dose vaccinates were serologically positive by at least one standard test. HIGT failed to detect any cattle as serologic reactors. All cattle were seronegative by ELISA by 5 months after vaccination.

Cover image of the 18th Volume of the Bovine Practitioner: Oklahoma State Capitol—the only State Capitol building in the country with a producing oil well.

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Published

1983-11-01

Issue

No. 18 (1983 November)

Section

Articles

How to Cite

Antibody responses of heifers vaccinated with reduced doses of Brucella abortus strain 19. (1983). The Bovine Practitioner, 1983(18), 174-178. https://doi.org/10.21423/bovine-vol1983no18p174-178

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