Immunological response of dairy cattle housed at an Ontario animal exhibit to vaccination with Escherichia coli O157 type III secreted proteins

Authors

  • Glenn G. Smith Ottawa Valley Veterinary Professional Corporation, 2257 County Rd #31, Winchester, ON, KOC 2K0
  • Susan E. Goebel Bioniche Life Sciences, Inc., 231 Dundas St. E., Belleville, ON, K8N 1E2
  • Louis A. Guilbault BlOptima Consulting, Inc, 529, rue Jodoin, Saint-Bruno, Québec, J3V 6G8
  • Louisa J. Zak Bioniche Life Sciences, Inc., 231 Dundas St. E., Belleville, ON, K8N 1E2
  • Xiaogang Li Bioniche Life Sciences, Inc., 231 Dundas St. E., Belleville, ON, K8N 1E2

DOI:

https://doi.org/10.21423/bovine-vol46no1p10-16

Keywords:

dairy, E. coli, O157, vaccination, antibodies, bacterial proteins, blood analysis, calves, cattle housing, cohort studies, cows, dairy cattle, dairy cows, disease transmission, dosage, immune response, on-farm production, public health, risk, vaccines, zoonoses

Abstract

Interventions to reduce on-farm risk are important to help decrease the likelihood that the public will come into contact with Escherichia coli O157. Dairy cattle housed at an Ontario animal exhibit were immunized against E. coli O157, and their blood was tested to measure antibody titers to type III secretory proteins in the vaccine. Data collected during this retrospective study supports the conclusions that all animals, including young calves, immunologically responded to vaccination. At the end of a nine-month study period, those animals which received a two-dose vaccination protocol had similar antibody titers to the type III secretory proteins as those administered a three-dose protocol, and all animals immunologically responded to a single annual booster dose of vaccine.

Cover image of Volume 46, No.1 of the Bovine Practitioner: a photo of a herd of cattle being herded by a man on a palomino horse across a field in Florida. Photo provided courtesy of Deseret Cattle and Citrus, St. Cloud, Florida.

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Published

2012-05-31

How to Cite

Smith, G. G., Goebel, S. E., Guilbault, L. A., Zak, L. J., & Li, X. (2012). Immunological response of dairy cattle housed at an Ontario animal exhibit to vaccination with Escherichia coli O157 type III secreted proteins. The Bovine Practitioner, 46(1), 10–16. https://doi.org/10.21423/bovine-vol46no1p10-16

Issue

Vol. 46, No. 1 (2012 Spring)

Section

Articles