Effects of parenteral or intranasal modified-live virus respiratory vaccination and revaccination on day 14 in auction-derived feedlot heifers

Authors

  • Erica Auchard Department of Agricultural Sciences, West Texas A&M University, Canyon, TX 79016
  • Deana V. Hardee Merck Animal Health, Madison, NJ 07940
  • Wally C. Koers Bos Technica Research Services Inc., Salina, KS 67401
  • Shane Davis Bos Technica Research Services Inc., Salina, KS 67401
  • Tim R. Parks Merck Animal Health, Madison, NJ 07940
  • John T. Richeson Department of Agricultural Sciences, West Texas A&M University, Canyon, TX 79016

DOI:

https://doi.org/10.21423/bovine-vol58no1p33-40

Keywords:

intranasal, parenteral, vaccination, bovine respiratory

Abstract

Auction-derived beef heifers were received in 12 arrival blocks and randomized to 4 treatment groups: 1) parenteral MLV vacci­nation on d 0 (INJ), 2) intranasal MLV vaccination on d 0 (INT), 3) parenteral MLV vaccination on d 0 and revaccination with intranasal on d 14 (INJ-R), 4) intranasal MLV vaccination on d 0 and revaccination with intranasal on d 14 (INT-R). Pen was experimental unit, with 12 pens/treatment and 65 to 76 heif­ers/pen in a randomized complete block design. Performance, health, carcass traits and BRSV and H. somni frequency of car­riage in the nasopharynx of revaccinated groups on d 0 and 60 was determined. Morbidity (P = 0.95), mortal­ity (P = 0.80), and other health variables (P > 0.74) did not dif­fer. However, an improvement in gain-to-feed (G:F) (P = 0.04), increased ribeye area (REA) (P ≤ 0.01) and percentage of edible livers (P ≤ 0.01) was observed for INJ and INJ-R. The BRSV (P = 0.09) and H. somni (P < 0.01) frequency of carriage in the naso­pharynx increased with time but no treatment effect (P ≥ 0.23) nor treatment x day interaction (P ≥ 0.29) existed. Revaccina­tion with an intranasal MLV did not impact health or growth, and arrival intranasal vaccination (INT and INT-R) resulted in less G:F and REA concomitant with increased liver absces­sation, compared to parenteral (INJ and INJ-R). Detection of H. somni in the nasopharynx was frequent on d 60, suggesting important prevalence of this bacterial pathogen in the south­ern U.S. cattle population.

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Published

2024-02-24

How to Cite

Auchard, E., Hardee, D. V., Koers, W. C., Davis, S., Parks, T. R., & Richeson, J. T. (2024). Effects of parenteral or intranasal modified-live virus respiratory vaccination and revaccination on day 14 in auction-derived feedlot heifers. The Bovine Practitioner, 58(1), 33–40. https://doi.org/10.21423/bovine-vol58no1p33-40

Issue

Section

Research Article