Effect of prepartum energy balance on neutrophil function following pegbovigrastim treatment in periparturient cows

Authors

  • Scott McDougall Cognosco, AnexaFVC, Morrinsville, New Zealand
  • Paul Rapnicki Elanco Animal Health, Greenfield, IN 46140
  • Stephen LeBlanc Ontario Veterinary College, University of Guelph, Guelph, ON, Canada
  • Axel Heiser AgResearch, Hopkirk Research Institute, Palmerston North, New Zealand

DOI:

https://doi.org/10.21423/aabppro20173391

Keywords:

periparturient, undernutrition, neutrophil

Abstract

Treatment with granulocyte colony stimulating factor (GCSF) increases neutrophil (PMN) count and enhances PMN function in the periparturient cow. It was hypothesized that prepartum undernutrition might reduce the effect of a commercial recombinant bovine G-CSF product (pegbovigrastim; Imrestor (IMR), Elanco) on PMN count and function. Hence the objective of this study was to test the effect of undernutrition for 1 month prior to calving on the response to IMR.

Cover image of the 50th Conference Proceedings: Text of "AABP Annual Conference" with the AABP logo superimposed over an interlocking 50. Yellow background.

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Published

2017-09-14

Issue

2017

Section

Posters

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