In vitro efficacy of anti-protozoal compounds as a novel treatment for Tritrichomonas foetus in bulls
DOI:
https://doi.org/10.21423/aabppro20163432Abstract
Currently, there are no legal treatments in the United States for cattle infected with Tritrichomonas foetus. This obligate parasite of the reproductive tract of the bovid creates serious economic loss in the cattle industry in the United States. The hypothesis of this study was that benzimidazoles (oxibendazole or oxfendazole) or ponazuril combined with a polymer enhancer, specifically polymer lecithin organogel (PLO), in a topical formulation may be an effective treatment for bulls infected with r foetus. Three in vitro experiments were performed to evaluate the antiprotozoal effects of the benzimidazole and ponazuril formulations, and all involved components on the growth of r foetus organisms.