Pharmacokinetics of hetacillin in dairy cattle following 3X milking

Authors

  • D. A. Lindquist Dept. of Population Health & Pathohiology, North Carolina State University, Raleigh, NC, 27607
  • R. E. Baynes Dept. of Population Health & Pathohiology, North Carolina State University, Raleigh, NC, 27607
  • G. W. Smith Dept. of Population Health & Pathohiology, North Carolina State University, Raleigh, NC, 27607

DOI:

https://doi.org/10.21423/aabppro20143728

Keywords:

mastitis, intramammary antibiotics, Hetacin-K®, milking interval

Abstract

Mastitis remains a critical disease in the dairy industry and the use of intramammary antibiotics plays a critical role in mastitis treatment. Hetacin-K® (Boehringer Ingelheim Vetmedica, Inc) is currently approved as an intramammary antibiotic that is used to treat mastitis in dairy cows. It is approved for once daily intramammary administration and can be used for a total of three days. More and more dairy farms are milking three times per day instead of the traditional two times per day; however, there is very little pharmacokinetic data on the use of intramammary drugs such as Hetacin-K® in a 3X system. The purpose of this study was to determine if once daily intramammary infusion of Hetacin-K® is sufficient to maintain therapeutic drug concentrations in cattle milked three times per day.

Cover image of the 47th Conference Proceedings: An image of a herd of cattle in a field at dusk. Three cows are standing in the foreground, looking adorable. Yellow background.

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Published

2014-09-18

Issue

2014

Section

Research Summaries 3

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