The Induction of a T Helper 1 Immune Response with an Inactivated Viral Vaccine

Authors

  • C. C. L. Chase Department of Veterinary Science, South Dakota State University, Brookings, SD
  • A. Young Department of Veterinary Science, South Dakota State University, Brookings, SD
  • A. Zimmerman Rural Technologies Inc, Brookings, SD
  • K. Gilkerson Rural Technologies Inc, Brookings, SD
  • K. Barling Novartis Animal Health, Larchwood, IA
  • D. Scholz Novartis Animal Health, Larchwood, IA

DOI:

https://doi.org/10.21423/aabppro20084470

Keywords:

Bovine viral diarrhea virus, BVDV, reproductive disease, respiratory disease, T helper 1, vaccines

Abstract

Bovine viral diarrhea virus (BVDV) is a major pathogen of cattle causing severe respiratory and reproductive disease. BVDV vaccines remain an important part of the control strategy. Inactivated vaccines have been often characterized as evoking only a humoral antibody response with little opportunity for memory. It has been well established that a good cell mediated response and memory requires a T helper 1 (TH1) response. In this study we measure the T helper 1 response in cattle vaccinated with Virashield.

Cover image of the 41st Conference Proceedings: A herd of cattle standing in the field, framed by a cloudy sky. Yellow background.

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Published

2008-09-25

Issue

2008

Section

Posters

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