Activity of Plasma-Protein C in Dairy Cows With Left-sided Displacement of the Abomasum and Fatty Liver Syndrome

Authors

  • J. Rehage Clinic for Diseases of Cattle, School of Veterinary Medicine; Bischofsholer Damm 15, D-3000 Hannover 1, Federal Republic of Germany
  • H. Scholz Clinic for Diseases of Cattle, School of Veterinary Medicine; Bischofsholer Damm 15, D-3000 Hannover 1, Federal Republic of Germany
  • J. Kramer Clinic for Diseases of Cattle, School of Veterinary Medicine; Bischofsholer Damm 15, D-3000 Hannover 1, Federal Republic of Germany
  • M. Mertens Clinic for Diseases of Cattle, School of Veterinary Medicine; Bischofsholer Damm 15, D-3000 Hannover 1, Federal Republic of Germany
  • W. Heuwieser Clinic for Diseases of Cattle, School of Veterinary Medicine; Bischofsholer Damm 15, D-3000 Hannover 1, Federal Republic of Germany
  • M. Höltershinken Clinic for Diseases of Cattle, School of Veterinary Medicine; Bischofsholer Damm 15, D-3000 Hannover 1, Federal Republic of Germany

DOI:

https://doi.org/10.21423/aabppro19926576

Keywords:

lipomobilisation, Fatty infiltration, plasma activity

Abstract

Fatty infiltration of the liver, occurring within 1 to 5 weeks postpartum, and due to excessive lipomobilisation, is the most common liver disease in dairy cows. Case studies showed that 91% of cases with left-sided displacement of the abomasum (LDA), accompanied by suppression of appetite and enhanced lipomobilisation, occurred during this period2. Our experience indicates that nearly 4% of cows with LOA, admitted for surgical treatment, develop hepatic failure in the postoperative period and die in hepatic coma or are slaughterd for that reason3.

It has been shown in humans that the plasma activity of Protein C, synthesized in the liver as a Vitamin K-dependant \ anticoagulant factor, decreases in severe liver disease. Therefore, dairy cows suffering from LDA were studied in order to gain information about the correlation between plasma-protein C-activity and hepatic lipidosis.

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Published

1992-08-31

Issue

Section

Digestive Dysfunction & Diseases

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